Matthew Goode as Matthew Clairmont – Millennia-old vampire and geneticist Matthew becomes concerned that his species could be at risk of extinction after several vampires fail to “sire” human beings. Only witch Diana Bishop will be able to help, and a spark soon forms between the pair
Teresa Palmer as Diana Bishop – Reluctant witch Diana tries to leave behind her supernatural background to focus on her academic career – but when she discovers a long-lost book, she’s pulled into an ancient conflict between witches, vampires and daemons.
Adetomiwa Edun as Sean – A human librarian working at Oxford’s Bodleian Library, and an old student friend of Diana Bishop’s.
Louise Brealey as Gillian Chamberlain – A fellow witch and academic alongside Diana at Oxford, Gillian has a much closer connection to other supernatural beings and urges Diana to rejoin the fold.
Owen Teale as Peter Knox – A high-ranking witch and representative on the Congregation, Knox tries his best to turn Diana to his cause.
Edward Bluemel as Marcus Whitmore – A vampire doctor, Marcus becomes concerned about his species’ failure to procreate. He is also Matthew’s son.
Aiysha Hart as Mirium Shephard – A vampire and lab colleague of Matthew, who is initially disapproving of his relationship with Diana.
Greg McHugh as Hamish Osborne – A daemon living within human society, Hamish is an old friend of Matthew’s.
Tanya Moodie as Agatha Wilson – Agatha is a daemon member of the supernatural organization, The Congregation.
Malin Buska as Satu Jarvinen – A Finnish witch and Congregation member, Satu plans to track down and capture Diana
Valarie Pettiford as Emily Mathers – Emily is a skilled witch and also the partner of Diana’s aunt, Sara
Alex Kingston as Sarah Bishop – The aunt and guardian of Diana, Sarah is a powerful witch in her own right and a frequent source of support for her niece.
310Daniel Ezra as Nathaniel Wilson – The son of Congregation member daemon Agatha Wilson, and husband to Aisling Loftus’ Sophie, Wilson is also the father to a young witch called Margaret
Aisling Loftus as Sophie Norman – The child of two witches, Sophie was nevertheless born a daemon, and is the wife of Nathaniel Wilso
Trystan Gravelle as Baldwin Montclair – Matthew’s vampire “brother”, son to Ysabeau and an investment banker of some success. He was turned into a vampire while living in Roman society, and uses a slightly altered version of the family name for business.
Greg Chillin as Dominico Michele – A real-life historical figure and former Doge of Venice, Domenico is presented in this series as an ancient vampire and former friend to Matthew, with a seat on the Congregation.
.Trevor Eve as Gerbert A’urillac – An ancient vampire, Gerbert has dark plans for Diana once he finds out her existence.
Lindsay Duncan as Ysabeau de Clermont – Matthew’s vampire “mother” and the matriarch of the de Clairmont clan, who lives in France and has a strong dislike of witches.
Elarica Johnson as Juliette Durand – A vampire turned and watched over by Gerbert, Juliette has a troubled past and a mysterious connection to Matthew.
Season 2 is in post production and will air sometime late in 2020